While Bee Propolis showed to be very effective in the treatment of infertility associated with mild endometriosis, caution should be exercised during time of pregnancy and breast-feeding. It is advised to avoid Bee Products - Honey, Bee Pollen and Royal Jelly - during pregnancy.

The effects of Propolis during pregnancy and breast-feeding have not been sufficiently evaluated, but since Propolis is known to be a sensitizing agent, it could cause development of allergies, therefore it is best not to use it during these times unless directed to do so by a physician.